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Quality
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INTENDED USE
The QuickScreen™ One-Step Rapid Opiates Test is a rapid, visual, qualitative,
competitive binding immunoassay for the detection of Opiates: Morphine, codeine,
heroin, opium and their metabolites in human urine. The test provides a fast
confirmation of the presence of Opiates in the subject sample at a
minimum cutoff sensitivity level of 2000 ng/ml, the revised sensitivity level set by the
National Institute on Drug Abuse and Departments of Health and Human Services.
Note: Where indicated, any positive test should be confirmed using quantitative
methods by a qualified testing laboratory. SUMMARY AND EXPLANATION OF THE TEST Opiates, often called narcotics, are analgesics (pain reducers) which work by depressing the central nervous system. They can also depress the respiratory system. Doctors often prescribe them for severe or chronic pain. Opiates are very addictive, both physically and psychologically. Use for only a short time normally results in addiction. Some commonly used opiates are: Codeine, Darvon, Heroin, Methadone, Morphine, Opium, Percodan, Talwin, Dilaudid and Demerol. Opiates are commonly referred to as "downers" . Opiates can appear in many forms: white powder or crystals; small white, yellow or orange pills; large colorful capsules; clear liquid and dark brown, sticky bars or balls. Heroin accounts for the majority of the illicit opiate abuse. Some physical indications of opiate use include: extreme loss of appetite and weight, needle tracks or punctures, black and blue marks from "skin popping", scars along veins, cramps, nausea, vomiting, excessive scratching and complaint of itching, excessive sweating, constipation, raw, red nostrils from snorting, runny nose, pin-point pupils and watery eyes, reduced vision, drowsiness, euphoria, trance-like states, excessive thirst, tremors, twitching, unkempt appearance, strong body odor, irritability, chills; slight hallucinations and lethargy. For comprehensive information on drug testing including typical half-life or drug detection periods see the Drug Testing FAQ. The QuickScreen™ One-Step Rapid Opiates Test utilizes a unique combination of monoclonal antibodies to
selectively identify Opiates and their major metabolites in urine with a high degree of
sensitivity. The test kit is a rapid, visually read screening method that does not require
special instrumentation or training.
PRINCIPLE
MATERIALS PROVIDED: Test Device and Dropper Pipette individually sealed in foil pouch with complete instructions. ASSAY PROCEDURE
INTERPRETATION OF TEST RESULTS:
Positive: One (1) pink-rose band appears in the control zone and no band appears in the test zone. A positive result indicates the Opiates level is
2000 ng/ml or higher in the test urine sample. The QuickScreen™ One-Step Rapid Opiates test is now available to professionals and individuals concerned with Opium based drug (see above) abuse. The test is one-step, fast, self-contained, individually packaged and can be performed any time the targeted drug use or abuse is suspected. The tests come in order units of five (5) individual tests at a cost per single diagnosis/screen of $4.00 for the minimum order unit. For testing situations where sample adulteration is suspect, a Rapid Urine Adulteration test is available.
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The QuickScreen™ One-Step Rapid Opiates Test technology incorporates a chromatographic absorbent device in which the drug or drug metabolites in the sample compete with a Opiates derivative immobilized on a porous membrane for limited antibody sites. This is the preferred scientific method for qualitative assay. In the assay procedure, urine mixes with labeled antibody-dye conjugate and migrates through test device. When Opiates levels are below
2000 ng/ml (the detection cutoff sensitivity of the test) unbound antibody-dye conjugate binds to immobilized antigen conjugate in the Test Zone ("T"), producing a pink-rose colored band that indicates a negative result. Conversely, when Opiates levels are above the detection limit, antibody-dye conjugate binds to the free drug, forming an antigen-antibody-dye complex. The complex competes with immobilized antigen conjugate in the Test Zone, preventing the development of a pink-rose colored band. Regardless of the test result, a color band is produced in the Control Zone ("C") by a non-specific sandwich dye conjugate reaction. This band serves as a built-in quality control by demonstrating antibody recognition, verifying that the reagents are chemically active, and confirming that the test was performed correctly.
