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PHENCYCLIDINE (PCP)
A.K.A. Angel Dust QuickScreen One-Step Rapid Drug Screen Test
(Cassette type)
A Professional, Forensic Diagnostic Test for use in the Qualitative Detection of
Phencyclidine and its Metabolites (PCP)
in Human Urine at a minimum sensitivity cut-off level of 25
ng/ml Established as Standard by the U.S. Department of Health and Human
Services, DOT, World Health Organization and
SAMHSA.
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INTENDED USE
For a comprehensive
discussion on drug of abuse testing including typical detection time periods
see the DRUG
TESTING FAQ |
The QuickScreen One-Step Rapid Phencyclidine Test is a rapid, qualitative, competitive binding immunoassay for the detection of Phencyclidine (PCP) metabolite in human urine. The test provides a fast
confirmation of the presence of Phencyclidines in the subject sample at a minimum cutoff sensitivity level of 25ng/ml Phencyclidine. Note: Any positive test should be confirmed using quantitative methods by a qualified healthcare professional.
Note: This assay
provides only a preliminary analytical test result. A more specific alternative chemical
method such as high-pressure liquid chromatography (HPLC) or Gas chromatography/mass
spectrometry (GC/MS) must be used in order to obtain a confirmed analytical result. For
test situations requiring laboratory confirmation by such methods please refer to the
QuickScreen Pro At Home Test Kit. Clinical consideration and professional
judgment should be applied to all test results, particularly when preliminary positive
results are indicated.
SUMMARY AND EXPLANATION OF THE TEST
Phencyclidine, commonly known as PCP or "angel dust" is used
primarily as a recreational drug for its hallucinogenic effects.
PCP is usually taken orally, by inhalation, insufflation or intravenously. It is
well absorbed by the body following all routes of administration concentrating
fastest in the fatty tissues and the brain. Unchanged PCP is excreted in the
urine in moderate amounts (10% of the dose). The terminal half-life for PCP
varies considerably with a range of 8-55 hours depending on quantity consumed,
body size, metabolic rate and other factors unique to the user. Statistically,
the average half-life is 18 hours. The effects of PCP, as with all
hallucinogens, are unpredictable and variable. Symptoms include euphoria,
extreme relaxation, increased strength, time and space distortions, anxiety,
panic, hallucination and extreme erratic behavior.
For comprehensive information on drug
testing including typical half-life or drug detection periods see the
Drug Testing FAQ.
For an
initial immunoassay result, a cutoff value of 25ng/ml total Phencyclidine metabolites is
required by the mandatory reference guidelines from the U.S. Department of Health and
Human Services.8 All presumptive positive results should be confirmed at a cutoff
concentration of 25 ng/ml Phencyclidine. The QuickScreen One-Step Phencyclidine Test
employs a unique combination of monoclonal antibodies to selectively identify
Phencyclidine and its derivative metabolites in urine with a high degree of sensitivity. The test kit is a rapid, visually
read screening test that does not require special instrumentation or technical
training and provides a fast indication
of recent Phencyclidine consumption.
PRINCIPLE
The QuickScreen One-Step Rapid Phencyclidine Test technology incorporates a chromatographic absorbent device in which the targeted drug or drug metabolites in the urine sample compete for limited antibody sites with an Phencyclidine control derivative immobilized on a porous membrane. This is the preferred scientific method for qualitative assay. In the assay procedure, urine mixes with a labeled antibody-dye conjugate and migrates through test device. When Phencyclidine levels are below 25 ng/ml (the detection cutoff sensitivity of the test) unbound antibody-dye conjugate binds to immobilized antigen conjugate in the Test Zone ("T"), producing a pink-rose colored band that indicates a negative result. Conversely, when Phencyclidine levels are above the detection limit, antibody-dye conjugate binds to the free drug, forming an antigen-antibody-dye complex. The complex competes with immobilized antigen conjugate in the Test Zone, preventing the development of a pink-rose colored band. Regardless of the test result, a color band is produced in the Control Zone ("C") by a non-specific sandwich dye conjugate reaction. This band serves as a built-in quality control by demonstrating antibody recognition, verifying that the reagents are chemically active, and confirming that the test was performed correctly.
MATERIALS
PROVIDED:
Phencyclidine (PCP0
Test
Device and Dropper Pipette individually sealed in foil pouch with complete instructions.
ASSAY
PROCEDURE
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Collect a urine sample from test subject using a suitable clean container preferably glass.
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Refrigerated specimens or other materials should be equilibrated to room temperature before testing.
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Open the foil pouch at the notch, remove the test device, and label the device with specimen ID.
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Holding the dropper vertically as shown, add
4 drops of urine into the sample well "S"
waiting 5 seconds between drops.
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Observe migration, or lateral flow of the sample across the entire test
panel. Add additional sample drops if migration is not complete.
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Positive results may be observed as soon as
5 minutes, depending on the concentration of
Phencyclidine in the tested specimen. To confirm negative results, a complete
reaction time of 8-10 minutes is required. Do not interpret results after
15 minutes.
INTERPRETATION
OF TEST RESULTS:
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Negative
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Positive
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Invalid
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The development of two lines, a control
line and a test line, in the test result window indicates a negative
test screen for the targeted drug or drug metabolite.
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The development of
only one line, the control line, in the test result window indicates a
positive test screen for the targeted drug or drug metabolite.
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The absence of a
control line in the test result window indicates an invalid test result
regardless of the presence of a test line in the test result window.
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Positive:
One (1) pink-rose band appears in the control zone and no band appears in the
test zone. A positive result indicates the PCP (Phencyclidine) level is
25 ng/ml or higher in the test urine
sample.
Negative: One
band appears in the test zone and one band appears in the control zone. A negative result indicates that the PCP (Phencyclidine) level is below the detection sensitivity of
25 ng/ml. IMPORTANT: any line, no matter how faint, appearing in the test area
confirms a negative test.
Invalid:
If there are no distinct color bands visible in both the test zone
and the control zone or if there is a visible band in the test zone but not in the control
zone, then the test is invalid. In this instance, re-testing of the specimen is
recommended.
TEST
AVAILABILITY
The QuickScreen One-Step Rapid Phencyclidine Test is now available to
professionals and individuals concerned with Phencyclidine abuse.
The test is one-step, fast,
self-contained, individually packaged and can be performed any time the targeted
drug use or abuse is suspected. The tests come in order units of five (5)
individual tests at a cost per single diagnosis/screen of $4.00 for the minimum
order unit. For testing situations where sample adulteration is suspect, a
Rapid Urine Adulteration test is available.
Description
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Sale Unit
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Cost
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QuickScreen
Rapid Phencyclidine (PCP) Cassette Test
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Five (5) Tests
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$19.90
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Fifteen (15) Tests
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$45.00
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Thirty (30) Tests
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$75.00
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One Hundred
(100) Tests
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$190.00
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Two Hundred
Fifty
(250) Tests |
$375.00 |
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*If the
order buttons are absent or inoperable, please use the
pricing overview page to order. |

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