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COCAINE (COC)
QuickScreen™ One-Step Rapid Drug Screen Test
(Cassette type)

A
Professional, Forensic Diagnostic Test for use in the Qualitative Detection of Cocaine
and Cocaine Metabolite in Human Urine at the Standard Sensitivity Cut-off level
of 300ng/ml Established as Standard by the U.S. Department of Health and Human
Services, DOT, World Health Organization and
SAMHSA. |
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INTENDED USE
For a comprehensive
discussion on drug of abuse testing including typical detection time periods
see the DRUG
TESTING FAQ |
The QuickScreen™ One-Step Rapid Cocaine Test is a rapid, visual, qualitative, competitive binding immunoassay for the detection of Cocaine (Erythyroxine Coca) metabolites (benzoylecgonine) in urine. The test provides a fast confirmation of the presence of Cocaine in the subject sample at a minimum cutoff sensitivity level of 300 ng/ml COC, the sensitivity level set by the National Institute on Drug Abuse. Note: Any positive test should be confirmed using quantitative methods by a qualified healthcare professional.
Note: This
assay provides only a preliminary analytical test
result. A more specific alternative chemical method such as high-pressure liquid
chromatography (HPLC) or Gas chromatography/mass spectrometry (GC/MS) must be used in
order to obtain a confirmed analytical result. For test situations requiring laboratory
confirmation by such methods please refer to the QuickScreen Pro At Home Test Kit. Clinical consideration and professional judgment should be applied to all
test results, particularly when preliminary positive results are indicated.
SUMMARY
AND EXPLANATION OF THE TEST
Cocaine is
an alkaloid present in Coca leaves (Erythyroxine coca). Its pharmacological properties,
such as stimulation of the brain and central nervous system plus its profound euphoric
effects, have been known for centuries. Cocaine has been used medicinally as a
local anesthetic agent, but its addictive properties have minimized its modern daily use.
Once considered a panacea for all sorts of ailments, Cocaine was readily available
as the principle ingredient in patent medicines sold over the counter in the late 1800s
and early 1900s. And indeed cocaine was the "secret" ingredient in the original
recipe for Coca-Cola©. Cocaine is most often self-administered by IV injection,
nasal insufflations (snorting), and inhalation of vapor from the heating of the free base
(smoking). The availability of crack (a street form of the free base) has
increased cocaine use by the latter method. Body elimination of cocaine
is predominantly controlled by its bio-transformation. Very low concentrations of cocaine
are detected in urine during the initial several hours, however benzoylecgonine, a
hydrolytic degradation product or system metabolite of cocaine, persists in urine at a
detectable level for 48 hours. Immunoassay testing has been developed for the
determination of benzoylecgonine (cocaine metabolite) in urine at concentrations of 300
ng/ml or greater, the sensitivity cutoff level set by the National Institute on Drug
Abuse.
For comprehensive information on drug
testing including typical half-life or drug detection periods see the
Drug Testing FAQ.
The QuickScreen™ One-Step Rapid Cocaine Test utilizes a unique combination of monoclonal antibodies to
selectively identify cocaine and its major metabolites in urine with a high degree of
sensitivity. The test kit is a rapid, visually read screening method that does not require
special instrumentation or training.
PRINCIPLE
The QuickScreen™ One-Step Rapid Cocaine Test technology incorporates a chromatographic absorbent device in which the drug or drug metabolites in the sample compete with a Cocaine derivative immobilized on a porous membrane for limited antibody sites. This is the preferred scientific method for qualitative assay. In the assay procedure, urine mixes with labeled antibody-dye conjugate and migrates through test device. When Cocaine levels are below 300 ng/ml (the detection cutoff sensitivity of the test) unbound antibody-dye conjugate binds to immobilized antigen conjugate in the Test Zone ("T"), producing a pink-rose colored band that indicates a negative result. Conversely, when Cocaine levels are above the detection limit, antibody-dye conjugate binds to the free drug, forming an antigen-antibody-dye complex. The complex competes with immobilized antigen conjugate in the Test Zone, preventing the development of a pink-rose colored band. Regardless of the test result, a color band is produced in the Control Zone ("C") by a non-specific sandwich dye conjugate reaction. This band serves as a built-in quality control by demonstrating antibody recognition, verifying that the reagents are chemically active, and confirming that the test was performed correctly.
MATERIALS PROVIDED:
Test Device and Dropper Pipette
individually sealed in foil pouch with complete instructions.
ASSAY
PROCEDURE
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Collect a urine sample from test subject using a suitable clean container preferably glass.
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Refrigerated specimens or other materials should be equilibrated to room temperature before testing.
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Open the foil pouch at the notch, remove the test device, and label the device with specimen ID.
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Holding the dropper vertically as shown, add
4 drops of urine into the sample well "S"
waiting 5 seconds between drops.
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Observe migration, or lateral flow of the sample across the entire test
panel. Add additional sample drops if migration is not complete.
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Positive results may be observed as soon as
5 minutes, depending on the concentration of
Benzoylecgonine in the tested specimen. To confirm negative results, a complete
reaction time of 8-10 minutes is required. Do not interpret results after
15 minutes.
INTERPRETATION
OF TEST RESULTS:
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Negative
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Positive
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Invalid
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The development of two lines, a
control line and a test line, in the test result window indicates a
negative test screen for the targeted drug or drug metabolite.
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The development of only one line,
the control line, in the test result window indicates a positive test
screen for the targeted drug or drug metabolite.
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The absence of a control line in
the test result window indicates an invalid test result regardless of
the presence of a test line in the test result window.
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Positive: One (1)
pink-rose band appears in the control zone and no band appears in the test zone.
A positive result indicates the Cocaine level is 300ng/ml or higher in the test
urine sample.
Negative: One band appears in the test zone and one band appears in the control
zone. A negative result indicates that the Cocaine level is below the detection
sensitivity of 300ng/ml. IMPORTANT: any line, no matter how faint, appearing in
the test area confirms a negative test.
Invalid If there are no distinct color bands visible in both the test zone and
the control zone or if there is a visible band in the test zone but not in the
control zone, then the test is invalid. In this instance, re-testing of the
specimen is recommended.
TEST AVAILABILITY
The QuickScreen™ One-Step Rapid Cocaine Test is now available to professionals
and individuals concerned with Cocaine abuse. The test
is one-step, fast, self-contained, individually packaged and can be performed
any time the targeted drug use or abuse is suspected. The tests come in order
units of five (5) individual tests at a cost per single diagnosis/screen of
$4.00 for the minimum order unit. For testing situations where sample
adulteration is suspect, a Rapid Urine
Adulteration test is available.
Test Description/Type |
Quantity |
Cost |
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QuickScreen
Cocaine (COC) Cassette Test |
Five
(5) Tests |
$19.90 |
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Fifteen
(15) Tests |
$45.00 |
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Thirty
(30) Tests |
$75.00 |
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One Hundred
(100) Tests |
$190.00 |
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Two Hundred
Fifty
(250) Tests |
$375.00 |
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*If the
order buttons are absent or inoperable, please use the
pricing overview page to order. |

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